Browsing the archives for the Nih tag.

Why is Cyclobenzaprine classed as a tricyclic antidepressant if it isn’t (ever?) prescribed for depression?

Imipramine
Imipramine
Kynysca asked:


From what I understand, it is typically indicated for pain, occassionally as a sleep aid. Also, that it isn’t even used for more than a couple weeks at a time. It is structurally similar to amitriptyline and imipramine, but never (from what I can see) prescribed for mood disorders. Why not? Perhaps I am missing something?
Thanx, Troy. Makes sense. I haven’t read anything reliable.

Wikipedia, at least, lists it as a tricyclic antidepressant:

http://en.wikipedia.org/wiki/Cyclobenzaprine

This research seems to list it as a TCA:

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1540431

I can’t find anything “official”….
Troy, I have read “effects” of Cyclobenzaprine are comparable to a benzo. Could this drug be used as an anxiolytic? Is it, ever prescribed for this purpose?
Thanx, again, Troy. To be honest, I read the first paragraph of that research.

And, yeah, wiki is “off” a lot of the time.

I appreciate the edit, man :-).
I guess what I kinda got hooked up on is how cyclobenzaprine could be so structually similar to other TCA’s (even, despite it’s disparate class), yet not work similarly…

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