Does protonix lessen the effectivity of plavix if taken together?

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better and better asked:


My mom had a stent put in her mesenteric artery which had become blocked due to her arterosclerosis. She is taking plavix to avoid blockage and protonix for acidity, bloating and other discomforts. She has read about the medical controversy that protonix can inhibit the effectiveness of plavix, but her doctors have not heard of this. She is very concerned.

1 Comment

  1. canada_winnipeg_man  •  Jan 3, 2010 @4:35 am

    A report warns that taking the drug clopidogrel (brand name: Plavix), the second most popular drug in the world, with proton pump inhibitors (PPIs) can increase the risk for major cardiovascular problems by 50% and of having a heart attack by 74 %.

    The study reports that PPIs inhibit the effectiveness of clopidogrel, the number two prescription drug in the world, thus increasing the risk of a major cardiac event, such as heart attacks and strokes by 50 percent. Since PPIs mimic the effect of a variant gene, which also renders clopidogrel ineffective, this study further suggests a potential role for genetic testing.

    Your mother should talk to her cardiologist if she is taking plavix to avoid blockage and protonix for acidity, bloating and other discomforts.

    Take care always
    0iram

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