The only interaction taking both at the same time would be a food interaction.
Foods that have a high fiber content may interfere with the absorption of nortriptyline from the stomach. As a result, less nortriptyline would be available for the body to use and blood levels could become too low. This could make the drug less effective. High fiber foods include fruits, vegetables, and grains (bread, cereal, rice, and pasta). Let your doctor know if you have recently changed your diet to include more high fiber foods while you are taking nortriptyline. If the nortriptyline does not seem to be working properly, it may be helpful to adjust your diet. You may want to ask your healthcare provider about this potential interaction if you think you are having problems.
Maybe it is up to you.
No interactions were found for the drugs you selected.
You searched for interactions between the following drugs:
Nortriptyline
Sulfamethoxazole; Trimethoprim, SMX-TMP Oral Suspension